Next, translation is complete when the ribosome reaches a termination codon.
2.
The RSE element is ~ 300 bp in length and located downstream of the gag natural translational termination codon.
3.
In NMD, the mRNA transcript contains a premature termination codon ( PTC ) due to a nonsense mutation.
4.
SMG6 cleaves mRNA near the premature translocation-termination codons and requires UPF1 and SMG1 to reduce reporter mRNA levels.
5.
Nonsense Mediated decay is involved in detection and decay of mRNA transcripts which contain premature termination codons ( PTCs ).
6.
However, exons 7 and 8 ( the cytoplasmic tail ) are not translated due to an in-frame translation termination codon in exon 6.
7.
To date, roughly 350 mutations in " MYBPC3 " have been identified, and in large part, the mutations result in protein truncation, shifts in reading frames, and premature termination codons.
8.
The post-termination complex formed by the end of the termination step consists of mRNA with the termination codon at the A-site, an uncharged tRNA in the P site, and the intact 70S ribosome.
9.
It is unlikely that SRGAP2B and SRGAP2D are now functional as SRGAP2B has a markedly reduced expression in human brain compared to SRGAP2C and the transcripts produced by SRGAP2D lack two internal exons, leading to a premature termination codon
10.
Sometimes, the coat protein UGA termination codon is suppressed allowing translation of an 84 kDa CP-readthrough protein, which is believed to be required for virus transmission by its protist vector " P . graminis ".
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